Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9WUQ2 | Preb | Guanine nucleotide-exchange factor SEC12 (Mammalian … | Mus musculus (Mouse) | 417 aa |
Protein Details: Q9WUQ2 (Preb)
Protein Information
| Accession | Q9WUQ2 |
|---|---|
| Protein Names | Guanine nucleotide-exchange factor SEC12 (Mammalian guanine nucleotide exchange factor Sec12) (mSec12) (Prolactin regulatory element-binding protein) |
| Gene Symbol | Preb |
| Organism | Mus musculus (Mouse) |
| Length | 417 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34884899 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRRRGVELY11RAPFPLYALR21IDPKTGLLIA31AGGGGAAKTG41IKNGVHFLQL
51-10051ELINGCLSAS61LLHSHDTETR71ATMNLALAGD81ILAAGQDAQC91QLLRFQVHQQ
101-150101KGSKAEKSGS111KEQGPRQRKG121APPAEKKSGA131QVHPEGVELK141VKNLEAVQTD
151-200151FSNEPLQKVV161CFNHDNTLLA171TGGTDGHVRV181WKVPSLEKVL191EFKAHEGEIG
201-250201DLTLGPDGKL211VTVGWDFKAS221VWQKDQLVTQ231LQWQENGPAS241SNTPYRYQAC
251-300251RFGQVPDQLG261GLRLFTVQIP271HKRLRQPPPC281YLTAWDSSTF291LPLRTRSCGH
301-350301EVISCLSVSD311SGTFLGLGTV321TGSVAIYIAF331SLQRLYYVKE341AHGIVVTDVT
351-400351FLPEKGCGPK361LLGPHETALF371SVAVDSRCQL381HLLPSRRSVP391VWLLLLLCVG
401-417401LIIVTILLLQ411TAFPGFL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 56 | - | - | - |
Deep-Palm: 0.83
|
|
| 90 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
| 161 | - | - | - |
Deep-Palm: 0.70
|
|
| 250 | - | - | - |
Deep-Palm: 0.89
|
|
| 280 | - | - | - |
Deep-Palm: 0.85
|
|
| 298 | - | - | - |
Deep-Palm: 0.85
|
|
| 305 | - | - | - |
Deep-Palm: 0.94
|
|
| 357 | - | - | - |
Deep-Palm: 0.97
|
|
| 378 | - | - | - |
Deep-Palm: 0.96
|
|
| 398 | - | - | - |
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
6
Liver
Specificity: 0.857
6/6 (100.0%)
1
Brain
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.