Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9WV54 Asah1 Acid ceramidase (AC) (ACDase) (Acid … Mus musculus (Mouse) 394 aa

Protein Details: Q9WV54 (Asah1)

Protein Information
AccessionQ9WV54
Protein NamesAcid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]
Gene SymbolAsah1
OrganismMus musculus (Mouse)
Length394 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRGQSLLTWV11LAAAVTCAQA21QDVPPWTEDC31RKSTYPPSGP41TYRGPVPWHT
51-10051INLDLPPYKR61WHELLAQKAP71ALRILVNSIT81SLVNTFVPSG91KLMKMVDQKL
101-150101PGMIGSLPDP111FGEEMRGIAD121VTGIPLGEII131SFNIFYELFT141MCTSIITEDE
151-200151KGHLLHGRNM161DFGIFLGWNI171NNNTWVVTEE181LKPLTVNLDF191QRNNKTVFKA
201-250201TSFVGYVGML211TGFKPGLFSL221SLNERFSING231GYLGILEWMF241GRKDAQWVGF
251-300251ITRSVLENTT261SYEEAKNTLT271KTKIMAPVYF281ILGGKKSGEG291CVITRERKES
301-350301LDVYELDPKH311GRWYVVQTNY321DRWKNTLFID331DRRTPAKKCL341NHTTQKNLSF
351-394351ATIYDVLSTK361PVLNKLTVFT371TLMDVTKGQF381ESHLRDCPDP391CIGW
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
17 - - -
Deep-Palm: 0.88
30 - - -
Deep-Palm: 0.21
142 Linear amide C-N hydrolases choloylglycine hydrolase family
Brain (34200797)
-
Deep-Palm: 0.29
291 - -
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.97
339 - - -
Deep-Palm: 0.32
387 - -
Brain (35358180)
Deep-Palm: 0.02
391 - -
Brain (35358180)
GPS-Palm: 0.96
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
Brain
Specificity: 0.182
4/4 (100.0%)
3
Liver
Specificity: 0.136
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.682
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine