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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9WVK8 Cyp46a1; Cyp46 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) … Mus musculus (Mouse) 500 aa

Protein Details: Q9WVK8 (Cyp46a1)

Protein Information
Accession Q9WVK8
Protein Names Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1)
Gene Symbol Cyp46a1; Cyp46
Organism Mus musculus (Mouse)
Length 500 aa
Isoforms No isoforms
Related PMIDs 28526873 29733200
Database Sources dbPTM
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
Brain tissue
Specificity: 0.750
3/12 (25.0%)
1
Liver tissue
Specificity: 0.250
1/19 (5.3%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSPGLLLLGS11AVLLAFGLCC21TFVHRARSRY31EHIPGPPRPS41FLLGHLPYFW
51-10051KKDEDCGRVL61QDVFLDWAKK71YGPVVRVNVF81YKTSVIVTSP91ESVKKFLMST
101-150101KYNKDSKMYR111ALQTVFGERL121FGQGLVSECD131YGRWYKQRKV141MDLAFSRSSL
151-200151VSLMETFNEK161AEQLVEILEA171KADGQTPVSM181QDMLTCATID191ILAKAAFGME
201-250201TSMLLGAQKP211LSQAVKVMLE221GISASRNTLA231KFMPGKRKQL241REIRESIRLL
251-300251RQVGKDWVQR261RREALKRGED271MPADILTQIL281KAEEGAQDDE291VLLDNFVTFF
301-350301IAGHETSANH311LAFTVMELSR321QPEIVARLQA331EVDEVVGSKR341HLDYEDLGRL
351-400351QYLSQVLKES361LRLYPPAWGT371FRLLEEETLI381DGVRVPGNTP391LLFSTYVMGR
401-450401MDTYFEDPLT411FNPDRFGPGA421PKPRFTYFPF431SLGHRSCIGQ441QFAQMEVKVV
451-500451MAKLLQRIEF461RLVPGQRFGL471QEQATLKPLD481PVLCTLRPRG491WQPAPPPPPC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
19 Prediction (High) - -
20 Prediction (High) - -
129 Prediction (High) - -
437 Experimental Cytochrome P450 28526873
484 Experimental DBPTM Prediction (High) - 28526873
500 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons