Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y239 | NOD1 | Nucleotide-binding oligomerization domain-containing protein 1 … | Homo sapiens (Human) | 953 aa |
Protein Details: Q9Y239 (NOD1)
Protein Information
| Accession | Q9Y239 |
|---|---|
| Protein Names | Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4) |
| Gene Symbol | NOD1 |
| Organism | Homo sapiens (Human) |
| Length | 953 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEQGHSEME11IIPSESHPHI21QLLKSNRELL31VTHIRNTQCL41VDNLLKNDYF
51-10051SAEDAEIVCA61CPTQPDKVRK71ILDLVQSKGE81EVSEFFLYLL91QQLADAYVDL
101-150101RPWLLEIGFS111PSLLTQSKVV121VNTDPVSRYT131QQLRHHLGRD141SKFVLCYAQK
151-200151EELLLEEIYM161DTIMELVGFS171NESLGSLNSL181ACLLDHTTGI191LNEQGETIFI
201-250201LGDAGVGKSM211LLQRLQSLWA221TGRLDAGVKF231FFHFRCRMFS241CFKESDRLCL
251-300251QDLLFKHYCY261PERDPEEVFA271FLLRFPHVAL281FTFDGLDELH291SDLDLSRVPD
301-350301SSCPWEPAHP311LVLLANLLSG321KLLKGASKLL331TARTGIEVPR341QFLRKKVLLR
351-400351GFSPSHLRAY361ARRMFPERAL371QDRLLSQLEA381NPNLCSLCSV391PLFCWIIFRC
401-450401FQHFRAAFEG411SPQLPDCTMT421LTDVFLLVTE431VHLNRMQPSS441LVQRNTRSPV
451-500451ETLHAGRDTL461CSLGQVAHRG471MEKSLFVFTQ481EEVQASGLQE491RDMQLGFLRA
501-550501LPELGPGGDQ511QSYEFFHLTL521QAFFTAFFLV531LDDRVGTQEL541LRFFQEWMPP
551-600551AGAATTSCYP561PFLPFQCLQG571SGPAREDLFK581NKDHFQFTNL591FLCGLLSKAK
601-650601QKLLRHLVPA611AALRRKRKAL621WAHLFSSLRG631YLKSLPRVQV641ESFNQVQAMP
651-700651TFIWMLRCIY661ETQSQKVGQL671AARGICANYL681KLTYCNACSA691DCSALSFVLH
701-750701HFPKRLALDL711DNNNLNDYGV721RELQPCFSRL731TVLRLSVNQI741TDGGVKVLSE
751-800751ELTKYKIVTY761LGLYNNQITD771VGARYVTKIL781DECKGLTHLK791LGKNKITSEG
801-850801GKYLALAVKN811SKSISEVGMW821GNQVGDEGAK831AFAEALRNHP841SLTTLSLASN
851-900851GISTEGGKSL861ARALQQNTSL871EILWLTQNEL881NDEVAESLAE891MLKVNQTLKH
901-950901LWLIQNQITA911KGTAQLADAL921QSNTGITEIC931LNGNLIKPEE941AKVYEDEKRI
951-953951ICF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | CARD domain Death-like domain superfamily | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.93
|
|
| 59 | - | - | - |
Deep-Palm: 0.90
|
|
| 61 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.85
|
|
| 146 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.86
|
|
| 182 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.93
|
|
| 236 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.72
|
|
| 241 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.60
|
|
| 249 | SWISSPALM DBPTM CYSMODDB | NACHT domain | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.31
|
| 259 | - | - | - |
Deep-Palm: 0.91
|
|
| 303 | - | - | - |
Deep-Palm: 0.97
|
|
| 385 | - | - | - |
Deep-Palm: 0.92
|
|
| 388 | - | - | - |
Deep-Palm: 0.66
|
|
| 394 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.15
|
|
| 400 | - | - | - |
Deep-Palm: 0.22
|
|
| 417 | - | - | - |
Deep-Palm: 0.71
|
|
| 461 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.84
|
|
| 558 | - | - | - |
Deep-Palm: 0.43
|
|
| 567 | - | - | - |
Deep-Palm: 0.91
|
|
| 593 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.70
|
|
| 658 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.42
|
|
| 676 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.79
|
|
| 685 | - | - | - |
Deep-Palm: 0.72
|
|
| 688 | - | - | - |
Deep-Palm: 0.30
|
|
| 692 | - | - | - |
Deep-Palm: 0.68
|
|
| 726 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.90
|
|
| 783 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.97
|
|
| 930 | - | - | - |
Deep-Palm: 0.90
|
|
| 952 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 144 | V → Cfs*33 | 0.002288 | DEL | Frame Shift Del | STAD |
| 173 | S → C | 0.002545 | SNP | Missense Mutation | GBM |
| 235 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 297 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 297 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 425 | F → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 572 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 591 | F → C | 0.002294 | SNP | Missense Mutation | OV |
| 617 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 676 | C → C | 0.002545 | SNP | Silent | GBM |
| 783 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 59* | C → ? | 0.002294 | SNP | Nonsense Mutation | OV |