Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y282-2 | ERGIC3 | Endoplasmic reticulum-Golgi intermediate compartment protein … | Homo sapiens (Human) | 230 aa |
Protein Details: Q9Y282-2 (ERGIC3)
Protein Information
| Accession | Q9Y282-2 |
|---|---|
| Protein Names | Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84) |
| Gene Symbol | ERGIC3 |
| Organism | Homo sapiens (Human) |
| Length | 230 aa |
| Isoforms | |
| Related PMIDs | 29575903 31251020 32651440 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEALGKLKQF11DAYPKTLEDF21RVKTCGGATV31TIVSGLLMLL41LFLSELQYYL
51-10051TTEVHPELYV61DKSRGDKLKI71NIDVLFPHMP81CAYLSIDAMD91VAGEQQLDVE
101-150101HNLFKQRLDK111DGIPVSSEAE121RHELGKVEVT131VFDPDSLDPD141RCESCYGAEA
151-200151EDIKCCNTCE161DVREAYRRRG171WAFKNPDTIE181QCRREGFSQK191MQEQKNEGCQ
201-230201VYGFLEVNKV211AGNFHFAPGK221SFQQSHVHGE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 25 | Endoplasmic reticulum vesicle transporter, N-terminal Endoplasmic reticulum vesicle transporter | - | - |
Deep-Palm: 0.95
|
|
| 81 | - | - | - |
Deep-Palm: 0.18
|
|
| 142 | - | - | - |
Deep-Palm: 0.08
|
|
| 145 | - | - | - |
Deep-Palm: 0.02
|
|
| 155 | - | - | - |
Deep-Palm: 0.04
|
|
| 156 | - | - | - |
Deep-Palm: 0.04
|
|
| 159 | - | - | - |
Deep-Palm: 0.16
|
|
| 182 | - | - | - |
Deep-Palm: 0.42
|
|
| 199 | - | - | - |
Deep-Palm: 0.35
|
|
| 349 | - | - | - |
Deep-Palm: 0.52
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
LNCaP
Specificity: 0.400
4/4 (100.0%)
4
PC3
Specificity: 0.400
4/4 (100.0%)
1
HeLa cell
Specificity: 0.100
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 48 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 141 | R → C | 0.002294 | SNP | Missense Mutation | OV |
| 141 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 155 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |