Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y2X3 | NOP58; NOL5; NOP5; HSPC120 | Nucleolar protein 58 (Nucleolar protein … | Homo sapiens (Human) | 529 aa |
Protein Details: Q9Y2X3 (NOP58)
Protein Information
| Accession | Q9Y2X3 |
|---|---|
| Protein Names | Nucleolar protein 58 (Nucleolar protein 5) |
| Gene Symbol | NOP58; NOL5; NOP5; HSPC120 |
| Organism | Homo sapiens (Human) |
| Length | 529 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29733200 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.543
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.543
25/46 (54.3%)
10
HAP1 cells
Specificity: 0.217
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.087
4/25 (16.0%)
4
293T cells
Specificity: 0.087
4/10 (40.0%)
2
PC3 cells
Specificity: 0.043
2/4 (50.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLVLFETSVG11YAIFKVLNEK21KLQEVDSLWK31EFETPEKANK41IVKLKHFEKF
51-10051QDTAEALAAF61TALMEGKINK71QLKKVLKKIV81KEAHEPLAVA91DAKLGGVIKE
101-150101KLNLSCIHSP111VVNELMRGIR121SQMDGLIPGV131EPREMAAMCL141GLAHSLSRYR
151-200151LKFSADKVDT161MIVQAISLLD171DLDKELNNYI181MRCREWYGWH191FPELGKIISD
201-250201NLTYCKCLQK211VGDRKNYASA221KLSELLPEEV231EAEVKAAAEI241SMGTEVSEED
251-300251ICNILHLCTQ261VIEISEYRTQ271LYEYLQNRMM281AIAPNVTVMV291GELVGARLIA
301-350301HAGSLLNLAK311HAASTVQILG321AEKALFRALK331SRRDTPKYGL341IYHASLVGQT
351-400351SPKHKGKISR361MLAAKTVLAI371RYDAFGEDSS381SAMGVENRAK391LEARLRTLED
401-450401RGIRKISGTG411KALAKTEKYE421HKSEVKTYDP431SGDSTLPTCS441KKRKIEQVDK
451-500451EDEITEKKAK461KAKIKVKVEE471EEEEKVAEEE481ETSVKKKKKR491GKKKHIKEEP
501-529501LSEEEPCTST511AIASPEKKKK521KKKKRENED
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 106 | Prediction (Medium) | - | - |
| 139 | Prediction (Medium) | - | - |
| 205 | CYSMODDB SWISSPALM DBPTM Prediction (High) | snoRNA binding domain fibrillarin | - |
| 207 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 120 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 120 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 149 | Y → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 342 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 371 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 431 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 439 | C → S | 0.003559 | SNP | Missense Mutation | KIRP |
| 443 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |