Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y3C5 | RNF11 | RING finger protein 11 | Homo sapiens (Human) | 154 aa |
Protein Details: Q9Y3C5 (RNF11)
Protein Information
| Accession | Q9Y3C5 |
|---|---|
| Protein Names | RING finger protein 11 |
| Gene Symbol | RNF11 |
| Organism | Homo sapiens (Human) |
| Length | 154 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNCLKSPTS11DDISLLHESQ21SDRASFGEGT31EPDQEPPPPY41QEQVPVPVYH
51-10051PTPSQTRLAT61QLTEEEQIRI71AQRIGLIQHL81PKGVYDPGRD91GSEKKIRECV
101-150101ICMMDFVYGD111PIRFLPCMHI121YHLDCIDDWL131MRSFTCPSCM141EPVDAALLSS
151-154151YETN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | DBPTM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
| 99 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.03
|
|
| 102 | - | - | - |
Deep-Palm: 0.05
|
|
| 117 | - | - | - |
Deep-Palm: 0.03
|
|
| 125 | - | - | - |
Deep-Palm: 0.02
|
|
| 136 | - | - | - |
Deep-Palm: 0.03
|
|
| 139 | - | - | - |
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
LNCaP
Specificity: 0.300
3/3 (100.0%)
3
Primary T cell
Specificity: 0.300
3/3 (100.0%)
3
PC3
Specificity: 0.300
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 136 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 139 | C → C | 0.005618 | SNP | Silent | PAAD |