Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y3E5 | PTRH2; BIT1; PTH2; CGI-147 | Peptidyl-tRNA hydrolase 2, mitochondrial (PTH … | Homo sapiens (Human) | 179 aa |
Protein Details: Q9Y3E5 (PTRH2)
Protein Information
| Accession | Q9Y3E5 |
|---|---|
| Protein Names | Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1) |
| Gene Symbol | PTRH2; BIT1; PTH2; CGI-147 |
| Organism | Homo sapiens (Human) |
| Length | 179 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 21076176 24357059 25914232 29733200 31251020 32944167 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.450
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
27
LNCaP cells
Specificity: 0.450
27/46 (58.7%)
10
293T cells
Specificity: 0.167
10/10 (100.0%)
8
Jurkat T cells
Specificity: 0.133
8/25 (32.0%)
4
HAP1 cells
Specificity: 0.067
4/10 (40.0%)
3
PC3 cells
Specificity: 0.050
3/4 (75.0%)
3
CEMx174 cells
Specificity: 0.050
3/3 (100.0%)
2
DU145 cells
Specificity: 0.033
2/2 (100.0%)
1
Endothelial cells
Specificity: 0.017
1/2 (50.0%)
1
Cerebral cortex
Specificity: 0.017
1/4 (25.0%)
1
Liver membrane
Specificity: 0.017
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPSKSLVMEY11LAHPSTLGLA21VGVACGMCLG31WSLRVCFGML41PKSKTSKTHT
51-10051DTESEASILG61DSGEYKMILV71VRNDLKMGKG81KVAAQCSHAA91VSAYKQIQRR
101-150101NPEMLKQWEY111CGQPKVVVKA121PDEETLIALL131AHAKMLGLTV141SLIQDAGRTQ
151-179151IAPGSQTVLG161IGPGPADLID171KVTGHLKLY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 25 | Prediction (Low) | - | - |
| 36 | Prediction (High) | - | - |
| 86 | Prediction (High) | - | - |
| 111 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 74 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |