Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y3E5 | PTRH2 | Peptidyl-tRNA hydrolase 2, mitochondrial (PTH … | Homo sapiens (Human) | 179 aa |
Protein Details: Q9Y3E5 (PTRH2)
Protein Information
| Accession | Q9Y3E5 |
|---|---|
| Protein Names | Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1) |
| Gene Symbol | PTRH2 |
| Organism | Homo sapiens (Human) |
| Length | 179 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 24357059 25914232 29733200 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPSKSLVMEY11LAHPSTLGLA21VGVACGMCLG31WSLRVCFGML41PKSKTSKTHT
51-10051DTESEASILG61DSGEYKMILV71VRNDLKMGKG81KVAAQCSHAA91VSAYKQIQRR
101-150101NPEMLKQWEY111CGQPKVVVKA121PDEETLIALL131AHAKMLGLTV141SLIQDAGRTQ
151-179151IAPGSQTVLG161IGPGPADLID171KVTGHLKLY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 25 | Prokaryotic membrane lipoprotein lipid attachment site profile. | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.81
|
|
| 28 | - | - | - |
Deep-Palm: 0.83
|
|
| 36 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.84
|
|
| 86 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.92
|
|
| 111 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.231
3
LNCaP
Specificity: 0.214
3/3 (100.0%)
3
CEM 174 cell
Specificity: 0.214
3/3 (100.0%)
2
Jurkat T cell
Specificity: 0.143
2/2 (100.0%)
2
293T cell
Specificity: 0.143
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.071
1/1 (100.0%)
1
heart
Specificity: 0.071
1/1 (100.0%)
1
HUVECs
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.071
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |