Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9Y3L5 RAP2C Ras-related protein Rap-2c (EC 3.6.5.2) Homo sapiens (Human) 183 aa

Protein Details: Q9Y3L5 (RAP2C)

Protein Information
AccessionQ9Y3L5
Protein NamesRas-related protein Rap-2c (EC 3.6.5.2)
Gene SymbolRAP2C
OrganismHomo sapiens (Human)
Length183 aa
IsoformsNo isoforms
Related PMIDs 19137006 19801377 22496122 24357059 26111759 29733200 31251020 31382980 32651440 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MREYKVVVLG11SGGVGKSALT21VQFVTGTFIE31KYDPTIEDFY41RKEIEVDSSP
51-10051SVLEILDTAG61TEQFASMRDL71YIKNGQGFIL81VYSLVNQQSF91QDIKPMRDQI
101-150101VRVKRYEKVP111LILVGNKVDL121EPEREVMSSE131GRALAQEWGC141PFMETSAKSK
151-183151SMVDELFAEI161VRQMNYSSLP171EKQDQCCTTC181VVQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
140 DBPTM SWISSPALM Ras family - -
GPS-Palm: 0.83
Deep-Palm: 0.98
176 DBPTM SWISSPALM - - -
GPS-Palm: 0.75
Deep-Palm: 0.02
177 DBPTM SWISSPALM - - -
GPS-Palm: 0.85
Deep-Palm: 0.02
180 - - -
GPS-Palm: 0.96
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
9
Jurkat T cell
Specificity: 0.391
9/9 (100.0%)
3
LNCaP
Specificity: 0.130
3/3 (100.0%)
3
Primary T cell
Specificity: 0.130
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.043
1/1 (100.0%)
1
U937 cell
Specificity: 0.043
1/1 (100.0%)
1
EC cell
Specificity: 0.043
1/1 (100.0%)
1
heart
Specificity: 0.043
1/1 (100.0%)
1
HUVECs
Specificity: 0.043
1/1 (100.0%)
1
DU145 cell
Specificity: 0.043
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.087
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine