Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y6K0 | CEPT1 | Choline/ethanolaminephosphotransferase 1 (hCEPT1) (EC 2.7.8.1) … | Homo sapiens (Human) | 416 aa |
Protein Details: Q9Y6K0 (CEPT1)
Protein Information
| Accession | Q9Y6K0 |
|---|---|
| Protein Names | Choline/ethanolaminephosphotransferase 1 (hCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22) |
| Gene Symbol | CEPT1 |
| Organism | Homo sapiens (Human) |
| Length | 416 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGHRSTRKR11CGDSHPESPV21GFGHMSTTGC31VLNKLFQLPT41PPLSRHQLKR
51-10051LEEHRYQSAG61RSLLEPLMQG71YWEWLVRRVP81SWIAPNLITI91IGLSINICTT
101-150101ILLVFYCPTA111TEQAPLWAYI121ACACGLFIYQ131SLDAIDGKQA141RRTNSSSPLG
151-200151ELFDHGCDSL161STVFVVLGTC171IAVQLGTNPD181WMFFCCFAGT191FMFYCAHWQT
201-250201YVSGTLRFGI211IDVTEVQIFI221IIMHLLAVIG231GPPFWQSMIP241VLNIQMKIFP
251-300251ALCTVAGTIF261SCTNYFRVIF271TGGVGKNGST281IAGTSVLSPF291LHIGSVITLA
301-350301AMIYKKSAVQ311LFEKHPCLYI321LTFGFVSAKI331TNKLVVAHMT341KSEMHLHDTA
351-400351FIGPALLFLD361QYFNSFIDEY371IVLWIALVFS381FFDLIRYCVS391VCNQIASHLH
401-416401IHVFRIKVST411AHSNHH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 11 | SWISSPALM DBPTM CYSMODDB | Prokaryotic membrane lipoprotein lipid attachment site profile. | - |
LNCaP
(31251020)
|
Deep-Palm: 0.03
|
| 30 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.82
|
| 98 | - | - | - |
Deep-Palm: 0.24
|
|
| 107 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.39
|
|
| 122 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.26
|
|
| 124 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.28
|
|
| 157 | - | - | - |
Deep-Palm: 0.33
|
|
| 170 | - | - | - |
Deep-Palm: 0.09
|
|
| 185 | - | - | - |
Deep-Palm: 0.02
|
|
| 186 | - | - | - |
Deep-Palm: 0.02
|
|
| 195 | - | - | - |
Deep-Palm: 0.02
|
|
| 253 | - | - | - |
Deep-Palm: 0.21
|
|
| 262 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.66
|
|
| 317 | - | - | - |
Deep-Palm: 0.57
|
|
| 388 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.15
|
|
| 392 | - | - | - |
Deep-Palm: 0.14
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
PC3
Specificity: 0.400
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 56 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 119 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 122 | C → S | 0.001014 | SNP | Missense Mutation | BRCA |
| 185 | C → Lfs*28 | 0.004577 | INS | Frame Shift Ins | STAD |
| 185 | C → Vfs*26 | 0.002288 | DEL | Frame Shift Del | STAD |
| 185 | C → Vfs*26 | 0.002747 | DEL | Frame Shift Del | LIHC |
| 185 | C → Vfs*26 | 0.002506 | DEL | Frame Shift Del | COAD |
| 185 | C → Lfs*28 | 0.002506 | INS | Frame Shift Ins | COAD |
| 185 | C → Vfs*26 | 0.007299 | DEL | Frame Shift Del | READ |
| 185 | C → Vfs*26 | 0.008130 | DEL | Frame Shift Del | THYM |
| 185 | C → Vfs*26 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 185 | C → Lfs*28 | 0.001887 | INS | Frame Shift Ins | UCEC |
| 191 | F → C | 0.003460 | SNP | Missense Mutation | CESC |
| 267 | R → C | 0.005660 | SNP | Missense Mutation | UCEC |
| 323 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |