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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9Y6M4-3 CSNK1G3 Casein kinase I isoform gamma-3 … Homo sapiens (Human) 423 aa

Protein Details: Q9Y6M4-3 (CSNK1G3)

Protein Information
AccessionQ9Y6M4-3
Protein NamesCasein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene SymbolCSNK1G3
OrganismHomo sapiens (Human)
Length423 aa
Isoforms
Related PMIDs 26111759 31251020
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MENKKKDKDK11SDDRMARPSG21RSGHNTRGTG31SSSSGVLMVG41PNFRVGKKIG
51-10051CGNFGELRLG61KNLYTNEYVA71IKLEPMKSRA81PQLHLEYRFY91KQLGSGDGIP
101-150101QVYYFGPCGK111YNAMVLELLG121PSLEDLFDLC131DRTFSLKTVL141MIAIQLISRM
151-200151EYVHSKNLIY161RDVKPENFLI171GRPGNKTQQV181IHIIDFGLAK191EYIDPETKKH
201-250201IPYREHKSLT211GTARYMSINT221HLGKEQSRRD231DLEALGHMFM241YFLRGSLPWQ
251-300251GLKADTLKER261YQKIGDTKRA271TPIEVLCENF281PEMATYLRYV291RRLDFFEKPD
301-350301YDYLRKLFTD311LFDRKGYMFD321YEYDWIGKQL331PTPVGAVQQD341PALSSNREAH
351-400351QHRDKMQQSK361NQVVSSTNGE371LNTDDPTAGR381SNAPITAPTE391VEVMDETNCQ
401-423401KVLNMWCCCF411FKRRKRKTIQ421RHK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
51 Phosphorylase Kinase - -
GPS-Palm: 0.95
Deep-Palm: 0.93
108 - - -
Deep-Palm: 0.95
130 - - -
Deep-Palm: 0.97
277 - - -
Deep-Palm: 0.90
407 - - -
GPS-Palm: 0.97
408 - - -
GPS-Palm: 0.98
409 - - -
GPS-Palm: 0.98
431 - - -
Deep-Palm: 0.72
432 - - -
Deep-Palm: 0.80
433 - - -
Deep-Palm: 0.69
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
LNCaP
Specificity: 0.667
4/4 (100.0%)
2
Jurkat T cell
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
52 G → C 0.001764 SNP Missense Mutation LUAD
64 Y → C 0.002506 SNP Missense Mutation COAD
236 G → C 0.001887 SNP Missense Mutation UCEC
288 R → C 0.002033 SNP Missense Mutation LUSC
288 R → C 0.001887 SNP Missense Mutation UCEC
445 R → C 0.002506 SNP Missense Mutation COAD
445 R → C 0.001887 SNP Missense Mutation UCEC