Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Y6M5 | SLC30A1 | Proton-coupled zinc antiporter SLC30A1 (Solute … | Homo sapiens (Human) | 507 aa |
Protein Details: Q9Y6M5 (SLC30A1)
Protein Information
| Accession | Q9Y6M5 |
|---|---|
| Protein Names | Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) (Zinc transporter 1) |
| Gene Symbol | SLC30A1 |
| Organism | Homo sapiens (Human) |
| Length | 507 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31251020 31382980 32944167 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCWGRNRGR11LLCMLALTFM21FMVLEVVVSR31VTSSLAMLSD41SFHMLSDVLA
51-10051LVVALVAERF61ARRTHATQKN71TFGWIRAEVM81GALVNAIFLT91GLCFAILLEA
101-150101IERFIEPHEM111QQPLVVLGVG121VAGLLVNVLG131LCLFHHHSGF141SQDSGHGHSH
151-200151GGHGHGHGLP161KGPRVKSTRP171GSSDINVAPG181EQGPDQEETN191TLVANTSNSN
201-250201GLKLDPADPE211NPRSGDTVEV221QVNGNLVREP231DHMELEEDRA241GQLNMRGVFL
251-300251HVLGDALGSV261IVVVNALVFY271FSWKGCSEGD281FCVNPCFPDP291CKAFVEIINS
301-350301THASVYEAGP311CWVLYLDPTL321CVVMVCILLY331TTYPLLKESA341LILLQTVPKQ
351-400351IDIRNLIKEL361RNVEGVEEVH371ELHVWQLAGS381RIIATAHIKC391EDPTSYMEVA
401-450401KTIKDVFHNH411GIHATTIQPE421FASVGSKSSV431VPCELACRTQ441CALKQCCGTL
451-500451PQAPSGKDAE461KTPAVSISCL471ELSNNLEKKP481RRTKAENIPA491VVIEIKNMPN
501-507501KQPESSL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
|
| 13 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.29
|
|
| 93 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.93
|
|
| 132 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.97
|
| 276 | - | - | - |
Deep-Palm: 0.10
|
|
| 282 | - | - | - |
Deep-Palm: 0.14
|
|
| 286 | - | - | - |
Deep-Palm: 0.08
|
|
| 291 | - | - | - |
Deep-Palm: 0.10
|
|
| 311 | - | - | - |
Deep-Palm: 0.15
|
|
| 321 | - | - | - |
Deep-Palm: 0.18
|
|
| 326 | - | - | - |
Deep-Palm: 0.42
|
|
| 390 | - | - | - |
Deep-Palm: 0.46
|
|
| 433 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.66
|
|
| 437 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.79
|
|
| 441 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.80
|
|
| 446 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.85
|
|
| 447 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.88
|
|
| 469 | - |
HeLa
(37611173)
|
LNCaP
(31251020)
|
GPS-Palm: 0.80
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.300
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
3
PC3
Specificity: 0.250
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.083
1/1 (100.0%)
1
U937 cell
Specificity: 0.083
1/1 (100.0%)
1
HeLa cell
Specificity: 0.083
1/1 (100.0%)
1
heart
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP cells (Mass)
Specificity: 0.083
1/4 (25.0%)
1
Cerebral Cortex (Mass)
Specificity: 0.083
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 164 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 282 | C → Lfs*8 | 0.001887 | INS | Frame Shift Ins | UCEC |
| 291 | C → Afs*5 | 0.002288 | DEL | Frame Shift Del | STAD |