Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9Z1M0 P2rx7 P2X purinoceptor 7 (P2X7) (ATP … Mus musculus (Mouse) 595 aa

Protein Details: Q9Z1M0 (P2rx7)

Protein Information
AccessionQ9Z1M0
Protein NamesP2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
Gene SymbolP2rx7
OrganismMus musculus (Mouse)
Length595 aa
IsoformsNo isoforms
Related PMIDs 29575903 29733200 31772009 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPACCSWNDV11LQYETNKVTR21IQSTNYGTVK31WVLHMIVFSY41ISFALVSDKL
51-10051YQRKEPVISS61VHTKVKGIAE71VTENVTEGGV81TKLGHSIFDT91ADYTFPLQGN
101-150101SFFVMTNYVK111SEGQVQTLCP121EYPRRGAQCS131SDRRCKKGWM141DPQSKGIQTG
151-200151RCVPYDKTRK161TCEVSAWCPT171EEEKEAPRPA181LLRSAENFTV191LIKNNIHFPG
201-250201HNYTTRNILP211TMNGSCTFHK221TWDPQCSIFR231LGDIFQEAGE241NFTEVAVQGG
251-300251IMGIEIYWDC261NLDSWSHHCR271PRYSFRRLDD281KNTDESFVPG291YNFRYAKYYK
301-350301ENNVEKRTLI311KAFGIRFDIL321VFGTGGKFDI331IQLVVYIGST341LSYFGLATVC
351-400351IDLLINTYSS361AFCRSGVYPY371CKCCEPCTVN381EYYYRKKCES391IMEPKPTLKY
401-450401VSFVDEPHIR411MVDQQLLGKS421LQVVKGQEVP431RPQMDFSDLS441RLSLSLHDSP
451-500451LTPGQSEEIQ461LLHEEVAPKS471GDSPSWCQCG481NCLPSRLPEQ491RRALEELCCR
501-550501RKPGRCITTS511KLFHKLVLSR521DTLQLLLLYQ531DPLLVLGEEA541TNSRLRHRAY
551-595551RCYATWRFGS561QDMADFAILP571SCCRWRIRKE581FPKTEGQYSG591FKYPY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.96
Deep-Palm: 0.02
5 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.02
119 - -
Brain (35358180)
Deep-Palm: 0.68
129 - - -
Deep-Palm: 0.17
135 - - -
Deep-Palm: 0.27
152 - - -
Deep-Palm: 0.25
162 - -
Brain (35358180)
Deep-Palm: 0.64
168 - -
Brain (35358180)
Deep-Palm: 0.96
216 - - -
Deep-Palm: 0.04
226 - -
Brain (35358180)
Deep-Palm: 0.10
260 - - -
Deep-Palm: 0.12
269 - - -
Deep-Palm: 0.04
350 - - -
Deep-Palm: 0.66
363 - - -
Deep-Palm: 0.05
371 - - -
Deep-Palm: 0.03
373 - -
Brain (35358180)
Deep-Palm: 0.02
374 - -
Brain (35358180)
Deep-Palm: 0.02
377 - -
Brain (35358180)
Deep-Palm: 0.02
388 - - -
Deep-Palm: 0.05
477 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
Deep-Palm: 0.42
479 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
Deep-Palm: 0.67
482 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
Deep-Palm: 0.85
498 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
GPS-Palm: 0.92
Deep-Palm: 0.96
499 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
GPS-Palm: 0.96
Deep-Palm: 0.98
506 DBPTM SWISSPALM P2X purinoreceptor 7 intracellular domain - -
Deep-Palm: 0.97
552 - - -
Deep-Palm: 0.48
572 - -
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.67
573 - -
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.62
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
Liver
Specificity: 0.176
3/3 (100.0%)
1
Raw 264.7
Specificity: 0.059
1/1 (100.0%)
1
Brain
Specificity: 0.059
1/1 (100.0%)
1
NSC
Specificity: 0.059
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
11
Brain tissue (Mass)
Specificity: 0.647
11/56 (19.6%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine