Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9Z2I0 | Letm1 | Mitochondrial proton/calcium exchanger protein (Electroneutral … | Mus musculus (Mouse) | 738 aa |
Protein Details: Q9Z2I0 (Letm1)
Protein Information
| Accession | Q9Z2I0 |
|---|---|
| Protein Names | Mitochondrial proton/calcium exchanger protein (Electroneutral mitochondrial K(+)/H(+)exchanger) (KHE) (Leucine zipper-EF-hand-containing transmembrane protein 1) |
| Gene Symbol | Letm1 |
| Organism | Mus musculus (Mouse) |
| Length | 738 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASILLRSCR11GRGPARLAPP21RAASPRGSLR31DRACLSCTRT41LGLTSRESVL
51-10051SRCCTPAHPV61YLCFKGEPLS71CWTQRPECQG81TAARTTWTPA91SARLVVTGPQ
101-150101YLPVRGWHSS111SPLGEDSVIE121KSLKSLKDKN131KKLEEGGPVY141SPPAQVVVRK
151-200151SLGQKVLDEL161RHYYHGFRLL171WIDTKIAARM181LWRILNGHTL191TRRERRQFLR
201-250201ICADLFRLVP211FLVFVVVPFM221EFLLPVVVKL231FPNMLPSTFE241TQSIKEERLK
251-300251KELRVKLELA261KFLQDTIEEM271ALKNKAAKGN281ATKDFSAFFQ291KIRETGERPS
301-350301NEEIMRFSKL311FEDELTLDNL321TRPQLVALCK331LLELQSIGTN341NFLRFQLTMR
351-400351LRSIKADDKL361ISEEGVDSLT371VKELQAACRA381RGMRALGVTE391DRLKGQLKQW
401-450401LDLHLHHEIP411TSLLILSRAM421YLPDTLSPAD431QLKSTLQTLP441EIVAKEAQVK
451-500451VAEVEGEKVD461NKAKLEATLQ471EEAAIQQEHL481EELKRASEAV491KDIQPEVAEA
501-550501TLPGRPGPEP511QPPVDDVILP521SEVLTDTAPV531LEGLKGEEIT541KEEIDILSDA
551-600551CSKLQEQKKS561LTKEKEELEL571LKEDVQDYSE581DLQEIKKELS591KTGEEKYIEE
601-650601SAASKRLSKR611VQQMIGQIDG621LITQLETTQQ631DGKLGPSQST641PTGESVISIT
651-700651ELISAMKQIK661HIPEHKLISL671TSALDDNKDG681NINIDDLVKV691IDLVNKEDVQ
701-738701ISTTQVAEIV711ATLEKEEKIE721EKEKAKEKAE731KEAAEVKN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.31
|
|
| 34 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.96
|
|
| 37 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.95
|
|
| 53 | - | - | - |
Deep-Palm: 0.94
|
|
| 54 | - | - | - |
Deep-Palm: 0.95
|
|
| 63 | - | - | - |
Deep-Palm: 0.33
|
|
| 71 | - | - | - |
Deep-Palm: 0.49
|
|
| 78 | - | - | - |
Deep-Palm: 0.45
|
|
| 202 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.95
|
|
| 329 | SWISSPALM DBPTM CYSMODDB | LETM1-like RBD |
Forebrain
(28680068)
|
Brain
(35358180)
|
Deep-Palm: 0.97
|
| 378 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
|
| 551 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
Liver
Specificity: 0.167
3/3 (100.0%)
2
Brain
Specificity: 0.111
2/2 (100.0%)
1
Testis
Specificity: 0.056
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.667
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.