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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
R4GNH3 PSMC3 26S proteasome regulatory subunit 6A … Homo sapiens (Human) 423 aa

Protein Details: R4GNH3 (PSMC3)

Protein Information
Accession R4GNH3
Protein Names 26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Tat-binding protein 1)
Gene Symbol PSMC3
Organism Homo sapiens (Human)
Length 423 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
6
LNCaP cells
Specificity: 0.667
6/46 (13.0%)
3
PC3 cells
Specificity: 0.333
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATVWDEAEQ11DGIGEEVLKM21STEEIIQRTR31LLDSEIKIMK41SEVLRVTHEL
51-10051QAMKDKIKEN61SEKIKVNKTL71PYLVSNVIEL81LDVDPNDQEE91DGANIDLDSQ
101-150101RKGKCAVIKT111STRQTYFLPV121IGLVDAEKLK131PGDLVGVNKD141SYLILETLPT
151-200151EYDSRVKAME161VDERPTEQYS171DIGGLDKQIQ181ELVEAIVLPM191NHKEKFENLG
201-250201IQPPKGVLMY211GPPGTGKTLL221ARACAAQTKA231TFLKLAGPQL241VQMFIGDGAK
251-300251LVRDAFALAK261EKAPSIIFID271ELDAIGTKRF281DSEKAGDREV291QRTMLELLNQ
301-350301LDGFQPNTQV311KVIAATNRVD321ILDPALLRSG331RLDRKIEFPM341PNEEARARIM
351-400351QIHSRKMNVS361PDVNYEELAR371CTDDFNGAQC381KAVCVEAGMI391ALRRGATELT
401-423401HEDYMEGILE411VQAKKKANLQ421YYA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
105 Prediction (Medium) - -
224 Prediction (High) - -
384 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
132 Y → C 0.001887 SNP Missense Mutation UCEC
264 G → C 0.002288 SNP Missense Mutation STAD
264 G → C 0.005435 SNP Missense Mutation ESCA
396 C → Y 0.001887 SNP Missense Mutation UCEC