Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| S4R3H4 | ACIN1 | Apoptotic chromatin condensation inducer 1 | Homo sapiens (Human) | 1283 aa |
Protein Details: S4R3H4 (ACIN1)
Protein Information
| Accession | S4R3H4 |
|---|---|
| Protein Names | Apoptotic chromatin condensation inducer 1 |
| Gene Symbol | ACIN1 |
| Organism | Homo sapiens (Human) |
| Length | 1283 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.923
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.923
36/46 (78.3%)
2
PC3 cells
Specificity: 0.051
2/4 (50.0%)
1
U937 cells
Specificity: 0.026
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAELEEVTLD11GKPLQALRVT21DLKAALEQRG31LAKSGQKSAL41VKRLKGALML
51-10051ENLQKHSTPH61AAFQPNSQIG71EEMSQNSFIK81QYLEKQQELL91RQRLEREARE
101-150101AAELEEASAE111SEDEMIHPEG121VASLLPPDFQ131SSLERPELEL141SRHSPRKSSS
151-200151ISEEKGDSDD161EKPRKGERRS171SRVRQARAAK181LSEGSQPAEE191EEDQETPSRN
201-250201LRVRADRNLK211TEEEEEEEEE221EEEDDEEEEG231DDEGQKSREA241PILKEFKEEG
251-300251EEIPRVKPEE261MMDERPKTRS271QEQEVLERGG281RFTRSQEEAR291KSHLARQQQE
301-350301KEMKTTSPLE311EEEREIKSSQ321GLKEKSKSPS331PPRLTEDRKK341ASLVALPEQT
351-400351ASEEETPPPL361LTKEASSPPP371HPQLHSEEEI381EPMEGPAPAV391LIQLSPPNTD
401-450401ADTRELLVSQ411HTVQLVGGLS421PLSSPSDTKA431ESPAEKVPEE441SVLPLVQKST
451-500451LADYSAQKDL461EPESDRSAQP471LPLKIEELAL481AKGITEECLK491QPSLEQKEGR
501-550501RASHTLLPSH511RLKQSADSSS521SRSSSSSSSS531SRSRSRSPDS541SGSRSHSPLR
551-600551SKQRDVAQAR561THANPRGRPK571MGSRSTSESR581SRSRSRSRSA591SSNSRKSLSP
601-650601GVSRDSSTSY611TETKDPSSGQ621EVATPPVPQL631QVCEPKERTS641TSSSSVQARR
651-700651LSQPESAEKH661VTQRLQPERG671SPKKCEAEEA681EPPAATQPQT691SETQTSHLPE
701-750701SERIHHTVEE711KEEVTMDTSE721NRPENDVPEP731PMPIADQVSN741DDRPEGSVED
751-800751EEKKESSLPK761SFKRKISVVS771ATKGVPAGNS781DTEGGQPGRK791RRWGASTATT
801-850801QKKPSISITT811ESLKSLIPDI821KPLAGQEAVV831DLHADDSRIS841EDETERNGDD
851-900851GTHDKGLKIC861RTVTQVVPAE871GQENGQREEE881EEEKEPEAEP891PVPPQVSVEV
901-950901ALPPPAEHEV911KKVTLGDTLT921RRSISQQKSG931VSITIDDPVR941TAQVPSPPRG
951-1000951KISNIVHISN961LVRPFTLGQL971KELLGRTGTL981VEEAFWIDKI991KSHCFVTYST
1001-10501001VEEAVATRTA1011LHGVKWPQSN1021PKFLCADYAE1031QDELDYHRGL1041LVDRPSETKT
1051-11001051EEQGIPRPLH1061PPPPPPVQPP1071QHPRAEQREQ1081ERAVREQWAE1091REREMERRER
1101-11501101TRSEREWDRD1111KVREGPRSRS1121RSRDRRRKER1131AKSKEKKSEK1141KEKAQEEPPA
1151-12001151KLLDDLFRKT1161KAAPCIYWLP1171LTDSQIVQKE1181AERAERAKER1191EKRRKEQEEE
1201-12501201EQKEREKEAE1211RERNRQLERE1221KRREHSRERD1231RERERERERD1241RGDRDRDRER
1251-12831251DRERGRERDR1261RDTKRHSRSR1271SRSTPVRDRG1281GRR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 860 | Prediction (Medium) | - | - |
| 994 | Prediction (Low) | - | - |
| 1165 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 256 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 425 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 578 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 587 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 661 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 691 | C → S | 0.001969 | SNP | Missense Mutation | HNSC |
| 833 | V → Cfs*39 | 0.002288 | DEL | Frame Shift Del | STAD |
| 895 | S → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 904 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 980 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1034 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 1188 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1280 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 1318 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1340 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1340 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1340 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1341 | R → C | 0.002506 | SNP | Missense Mutation | COAD |