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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
S4R3Z2 AKR1C3; hCG_19343 Aldo-keto reductase family 1 member … Homo sapiens (Human) 300 aa

Protein Details: S4R3Z2 (AKR1C3)

Protein Information
Accession S4R3Z2
Protein Names Aldo-keto reductase family 1 member C3 (Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_a)
Gene Symbol AKR1C3; hCG_19343
Organism Homo sapiens (Human)
Length 300 aa
Isoforms No isoforms
Related PMIDs 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Cerebral cortex
Specificity: 1.000
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQISQVPRSK11ALEVTKLAIE21AGFRHIDSAH31LYNNEEQVGL41AIRSKIADGS
51-10051VKREDIFYTS61KLWSTFHRPE71LVRPALENSL81KKAQLDYVDL91YLIHSPMSLK
101-150101PGEELSPTDE111NGKVIFDIVD121LCTTWEAMEK131CKDAGLAKSI141GVSNFNRRQL
151-200151EMILNKPGLK161YKPVCNQVEC171HPYFNRSKLL181DFCKSKDIVL191VAYSALGSQR
201-250201DKRWVDPNSP211VLLEDPVLCA221LAKKHKRTPA231LIALRYQLQR241GVVVLAKSYN
251-300251EQRIRQNVQV261FEFQLTAEDM271KAIDGLDRNL281HYFNSDSFAS291HPNYPYSDEY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
122 Prediction (Low) - -
183 CYSMODDB SWISSPALM DBPTM Prediction (Low) Aldo/keto reductase family -
219 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
47 R → C 0.001887 SNP Missense Mutation UCEC
87 S → C 0.003559 SNP Missense Mutation KIRP
154 C → F 0.001014 SNP Missense Mutation BRCA
170 R → C 0.001764 SNP Missense Mutation LUAD
170 R → C 0.003559 SNP Missense Mutation KIRP
193 C → R 0.002747 SNP Missense Mutation LIHC
276 R → C 0.001887 SNP Missense Mutation UCEC