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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
V9GYV7 PFKP Phosphofructokinase, platelet Homo sapiens (Human) 113 aa

Protein Details: V9GYV7 (PFKP)

Protein Information
AccessionV9GYV7
Protein NamesPhosphofructokinase, platelet
Gene SymbolPFKP
OrganismHomo sapiens (Human)
Length113 aa
IsoformsNo isoforms
Related PMIDs 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNAAVRAVVR11MGIYVGAKVY21FIYEGYQGMV31DGGSNIAEAD41WESVSSILQV
51-10051GGTIIGSARC61QAFRTREGRL71KAACNLLQRG81ITNLCVIGGD91GSLTGANLFR
101-113101KEWSGLLEEL111ARN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
60 - - -
GPS-Palm: 0.83
Deep-Palm: 0.96
74 - -
cerebral cortex (36430497)
GPS-Palm: 0.97
Deep-Palm: 0.97
85 SWISSPALM DBPTM CYSMODDB Phosphofructokinase
HeLa (29575903)
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.82
Deep-Palm: 0.96
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
3
PC3
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
44 R → C 0.002506 SNP Missense Mutation COAD
44 R → C 0.002141 SNP Missense Mutation SKCM
48 R → C 0.002288 SNP Missense Mutation STAD
48 R → C 0.002506 SNP Missense Mutation COAD
48 R → C 0.001887 SNP Missense Mutation UCEC
117 R → C 0.002288 SNP Missense Mutation STAD
118 G → C 0.002033 SNP Missense Mutation LUSC
343 C → C 0.004577 SNP Silent STAD
354 R → C 0.002288 SNP Missense Mutation STAD
354 R → C 0.001887 SNP Missense Mutation UCEC
440 G → C 0.001887 SNP Missense Mutation UCEC
563 C → C 0.001887 SNP Silent UCEC
576 R → C 0.002288 SNP Missense Mutation STAD