Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
V9GZ37 HSPA1A Heat shock protein family A … Homo sapiens (Human) 476 aa

Protein Details: V9GZ37 (HSPA1A)

Protein Information
Accession V9GZ37
Protein Names Heat shock protein family A (Hsp70) member 1A
Gene Symbol HSPA1A
Organism Homo sapiens (Human)
Length 476 aa
Isoforms No isoforms
Related PMIDs 19137006 21076176 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.828
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.828
24/46 (52.2%)
5
Jurkat T cells
Specificity: 0.172
5/25 (20.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAKAAAIGID11LGTTYSCVGV21FQHGKGERNV31LIFDLGGGTF41DVSILTIDDG
51-10051IFEVKATAGD61THLGGEDFDN71RLVNHFVEEF81KRKHKKDISQ91NKRAVRRLRT
101-150101ACERAKRTLS111SSTQASLEID121SLFEGIDFYT131SITRARFEEL141CSDLFRSTLE
151-200151PVEKALRDAK161LDKAQIHDLV171LVGGSTRIPK181VQKLLQDFFN191GRDLNKSINP
201-250201DEAVAYGAAV211QAAILMGDKS221ENVQDLLLLD231VAPLSLGLET241AGGVMTALIK
251-300251RNSTIPTKQT261QIFTTYSDNQ271PGVLIQVYEG281ERAMTKDNNL291LGRFELSGIP
301-350301PAPRGVPQIE311VTFDIDANGI321LNVTATDKST331GKANKITITN341DKGRLSKEEI
351-400351ERMVQEAEKY361KAEDEVQRER371VSAKNALESY381AFNMKSAVED391EGLKGKISEA
401-450401DKKKVLDKCQ411EVISWLDANT421LAEKDEFEHK431RKELEQVCNP441IISGLYQGAG
451-476451GPGPGGFGAQ461GPKGGSGSGP471TIEEVD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
102 Prediction (High) - -
141 Prediction (Medium) - -
438 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
626 G → C 0.001887 SNP Missense Mutation UCEC