Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
V9PBN7 AQP4 Aquaporin-4 Homo sapiens (Human) 296 aa

Protein Details: V9PBN7 (AQP4)

Protein Information
Accession V9PBN7
Protein Names Aquaporin-4
Gene Symbol AQP4
Organism Homo sapiens (Human)
Length 296 aa
Isoforms No isoforms
Related PMIDs 26876311 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
Prefrontal cortex
Specificity: 0.200
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSDRPTARRW11GKCGPLCTRE21NIMVAFKGVW31TQAFWKAVTA41EFLAMLIFVL
51-10051LSLGSTINWG61GTEKPLPVDM71VLISLCFGLS81IATMVQCFGH91ISGGHINPAV
101-150101TVAMVCTRKI111SIAKSVFYIA121AQCLGAIIGA131GILYLVTPPS141VVGGLGVTMV
151-200151HGNLTAGHGL161LVELIITFQL171VFTIFASCDS181KRTDVTGSIA191LAIGFSVAIG
201-250201HLFAIYWVGP211IIGAVLAGGL221YEYVFCPDVE231FKRRFKEAFS241KAAQQTKGSY
251-296251MEVEDNRSQV261ETDDLILKPG271VVHVIDVDRG281EEKKGKDQSG291EVLSSV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
13 Prediction (Medium) - -
17 Prediction (High) - -
76 Prediction (Low) - -
106 Prediction (High) - -
123 Prediction (Low) - -
178 Prediction (Low) - -
226 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
178 C → W 0.001887 SNP Missense Mutation UCEC