Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| V9PBN7 | AQP4 | Aquaporin-4 | Homo sapiens (Human) | 296 aa |
Protein Details: V9PBN7 (AQP4)
Protein Information
| Accession | V9PBN7 |
|---|---|
| Protein Names | Aquaporin-4 |
| Gene Symbol | AQP4 |
| Organism | Homo sapiens (Human) |
| Length | 296 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSDRPTARRW11GKCGPLCTRE21NIMVAFKGVW31TQAFWKAVTA41EFLAMLIFVL
51-10051LSLGSTINWG61GTEKPLPVDM71VLISLCFGLS81IATMVQCFGH91ISGGHINPAV
101-150101TVAMVCTRKI111SIAKSVFYIA121AQCLGAIIGA131GILYLVTPPS141VVGGLGVTMV
151-200151HGNLTAGHGL161LVELIITFQL171VFTIFASCDS181KRTDVTGSIA191LAIGFSVAIG
201-250201HLFAIYWVGP211IIGAVLAGGL221YEYVFCPDVE231FKRRFKEAFS241KAAQQTKGSY
251-296251MEVEDNRSQV261ETDDLILKPG271VVHVIDVDRG281EEKKGKDQSG291EVLSSV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.19
|
|
| 17 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.73
|
|
| 76 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.51
|
|
| 87 | - | - | - |
Deep-Palm: 0.19
|
|
| 106 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.70
|
|
| 123 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.88
|
|
| 178 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.75
|
|
| 226 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
frontal cortex
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 178 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |