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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
X5CKB3 TAP1 Antigen peptide transporter 1 (EC … Homo sapiens (Human) 748 aa

Protein Details: X5CKB3 (TAP1)

Protein Information
Accession X5CKB3
Protein Names Antigen peptide transporter 1 (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide transporter TAP1)
Gene Symbol TAP1
Organism Homo sapiens (Human)
Length 748 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
Jurkat T cells
Specificity: 0.375
3/25 (12.0%)
3
PC3 cells
Specificity: 0.375
3/4 (75.0%)
2
DU145 cells
Specificity: 0.250
2/2 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASSRCPAPR11GCRCLPGASL21AWLGTVLLLL31ADWVLLRTAL41PRIFSLLVPT
51-10051ALPLLRVWAV61GLSRWAVLWL71GACGVLRATV81GSKSENAGAQ91GWLAALKPLA
101-150101AALGLALPGL111ALFRELISWG121APGSADSTRL131LHWGSHPTAF141VVSYAAALPA
151-200151AALWHKLGSL161WVPGGQGGSG171NPVRRLLGCL181GSETRRLSLF191LVLVVLSSLG
201-250201EMAIPFFTGR211LTDWILQDGS221ADTFTRNLTL231MSILTIASAV241LEFVGDGIYN
251-300251NTMGHVHSHL261QGEVFGAVLR271QETEFFQQNQ281TGNIMSRVTE291DTSTLSDSLS
301-350301ENLSLFLWYL311VRGLCLLGIM321LWGSVSLTMV331TLITLPLLFL341LPKKVGKWYQ
351-400351LLEVQVRESL361AKSSQVAIEA371LSAMPTVRSF381ANEEGEAQKF391REKLQEIKTL
401-450401NQKEAVAYAV411NSWTTSISGM421LLKVGILYIG431GQLVTSGAVS441SGNLVTFVLY
451-500451QMQFTQAVEV461LLSIYPRVQK471AVGSSEKIFE481YLDRTPRCPP491SGLLTPLHLE
501-550501GLVQFQDVSF511AYPNRPDVLV521LQGLTFTLRP531GEVTALVGPN541GSGKSTVAAL
551-600551LQNLYQPTGG561QLLLDGKPLP571QYEHRYLHRQ581VAAVGQEPQV591FGRSLQENIA
601-650601YGLTQKPTME611EITAAAVKSG621AHSFISGLPQ631GYDTEVDEAG641SQLSGGQRQA
651-700651VALARALIRK661PCVLILDDAT671SALDANSQLQ681VEQLLYESPE691RYSRSVLLIT
701-748701QHLSLVEQAD711HILFLEGGAI721REGGTHQQLM731EKKGCYWAMV741QAPADAPE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
6 Prediction (Medium) - -
12 Prediction (Medium) - -
14 Prediction (Low) - -
73 Prediction (High) - -
179 Prediction (High) - -
315 Prediction (Low) - -
662 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
544 R → C 0.002506 SNP Missense Mutation COAD
544 R → C 0.003774 SNP Missense Mutation UCEC
547 R → C 0.002747 SNP Missense Mutation LIHC
575 R → C 0.002294 SNP Missense Mutation OV
589 R → C 0.002545 SNP Missense Mutation GBM